Bibliografia
Donald Metcalf

 

 

 

 1. Bradley TR and Metcalf D. The growth of mouse bone marrow cells in vitro. Aust. J. Exp. Biol. Med. 1966; 44: 287-300. 2. Ichikawa Y et al. In vitro control of the development of macrophage and granulocyte colonies. Proc. Natl. Acad. Sci. USA 1966; 56: 488-495. 3. Metcalf D. The Hemopoietic Colony Stimulating Factors. Amsterdam: Elsevier, 1984. 4. Metcalf D and Nicola NA. The hemopoietic colony stimulating factors. London: Cambridge University Press, 1995. 5. Metcalf D and Nicola NA. Direct proliferative actions of stem cell factor on murine bone marrow cells in vitro: effects of combination with colony-stimulating factors. Proc. Natl. Acad. Sci. USA 1991; 88: 6239-6243. 6. McKinstry W et al. Distribution of IL-6 receptors on murine hemopoietic and lymphoid cells and the anomalous action of IL-6 in stimulating granulocytic proliferation. Leukemia 1994; 8: 1726-1733. 7. Metcalf D et al. In vitro actions on hemopoietic cells of recombinant murine GM-CSF purified after production in Escherichia coli: Comparison with purified native GM-CSF. J.Cell. Physiol. 1986; 128: 421-431. 8. Metcalf D et al. The regulation of hematopoiesis in max 41 transgenic mice with sustained excess granulopoiesis. Leukemia 1996; 10: 311-320. 9. Metcalf D and Nicola NA. Proliferative effects of purified granulocyte colony-stimulating factor (G-CSF) on normal mouse hematopoietic cells. J. Cell. Physiol. 1983; 116: 198-206. 10. Metcalf D et al. Quantitative responsiveness of murine hemopoietic populations in vitro and in vivo to recombinant Multi-CSF (IL-3). Exp. Hematol. 1987; 15: 288-295. 11. Metcalf D and Nicola NA. The clonal proliferation of normal mouse hemopoietic cells: Enhancement and suppression by CSF combinations. Blood 1992; 79: 2861-2866. 12. Metcalf D. Clonal analysis of proliferation and differentiation of paired daughter cells: Action of granulocyte-macrophage colony-stimulating factor on granulocyte-macrophage precursors. Proc. Natl. Acad. Sci. USA 1980; 77: 5327-5330. 13. Metcalf D and Merchav S. Effects of GM-CSF deprivation on precursors of granulocytes and macrophages. J. Cell. Physiol. 1982; 112: 411-418. 14. Begley CG et al. Purified colony stimulating factor enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive microassay for colony stimulating factors. Blood 1986; 68: 162-166. 15. Williams GT et al. Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature (London) 1990; 343: 76-79. 16. Metcalf D et al. Clonal analysis of progenitor cell commitment to granulocyte or macrophage production. J. Cell. Physiol. 1982; 111: 275-282. 17. Valtieri M et al. Cytokine-dependent granulocytic differentiation: Regulation of proliferative and differentiative responses in a murine progenitor cell line. J. Immunol. 1987; 138: 3829-3835. 18. Grant SM and Heel RC. Recombinant granulocyte-macrophage colony-stimulating factor (rGM-CSF). Drugs 1992; 43: 516-560. 19. Hollingshead LM and Goa RL. Recombinant granulocyte colony-stimulating factor (rG-CSF). A review of its pharmacological properties and prospective role in neutropenic conditions. Drugs 1991; 42: 300-330. 20. Metcalf D et al. Production of hematopoietic regulatory factors in cultures of adult and fetal mouse organs: Measurement by specific bioassays. Leukemia 1995; 9: 1556-1564. 21. Layton JE et al. Evidence for a novel in vivo control mechanism of granulopoiesis: Mature cell-related control of a regulatory growth factor. Blood 1989; 74: 1303-1307. 22. Metcalf D et al. Effects of purified bacterially synthesized murine Multi-CSF (IL-3) on hematopoiesis in normal adult mice. Blood 1986; 68: 46-57. 23. Metcalf D et al. Hemopoietic responses in mice injected with purified recombinant murine GM-CSF. Exp. Hematol. 1987; 15: 1-9. 24. Molineux G et al. A comparison of hematopoiesis in normal and splenectomized mice treated with granulocyte colony-stimulating factor. Blood 1990; 75: 563-569. 25. Cole DJ et al. Phase I trial of recombinant human macrophage colony-stimulating factor administered by continuous intravenous infusion in patients with metastatic cancer. J. Natl. Cancer Instit. 1994; 86: 39-45. 26. Lord BI et al. Myeloid cell kinetics in mice treated with recombinant interleukin-3, granulocyte colony-stimulating (CSF), or granulocyte-macrophage CSF in vivo. Blood 1991; 77: 2154-2159. 27. de Haan G et al. Long-term recombinant human granulocyte colony-stimulating factor (rhG-CSF) treatment severely depresses murine marrow erythropoiesis without causing an anemia. Exp. Hematol. 1992; 20: 600-604. 28. Roberts AW and Metcalf D. Granulocyte colony-stimulating factor induces selective elevations of progenitor cells in the peripheral blood of mice. Exp. Hematol. 1994; 22: 1156-1163. 29. Cynshi O et al. Reduced response to granulocyte colony-stimulating factor in W/Wv and Sl/Sld mice. Leukemia 1991; 5: 75-77. 30. Postmus RE et al. Effects of recombinant interleukin-3 in patients with relapsed small-cell lung cancer treated with chemotherapy: A dose-finding study. J. Clin. Oncol. 1992; 10: 1131-1140. 31. Dührsen U et al. Effects of recombinant human granulocyte colony-stimulating factor on hemopoietic progenitor cells in cancer patients. Blood 1998; 72: 2074-2081. 32. Socinski MA et al. Granulocyte-macrophage colony-stimulating factor expands the circulating haemopoietic progenitor cell compartment in man. Lancet 1988; 1: 1194-1198. 33. Molineux G et al. Transplantation potential of peripheral blood stem cells induced by granulocyte colony-stimulating factor. Blood 1990; 76: 2153-2158. 34. Roberts AW et al. Genetic influences determining progenitor cell mobilization and leukocytosis induced by granulocyte colony-stimulating factor. Blood 1997; 89: 2736-2744. 35. Sheridan WP et al. Effect of peripheral-blood progenitor cells mobilized by Filgrastim (G-CSF) on platelet recovery after high-dose chemotherapy. Lancet 1992; 339: 640-644. 36. Matsumoto M et al. Protective effect of human granulocyte colony-stimulating factor on microbial infection in neutropenic mice. Infect. Immun. 1987; 55: 2715-2720. 37. Yasuda H et al. Therapeutic efficacy of granulocyte colony-stimulating factor alone and in combination with antibiotics against Pseudomonas aeruginosa infections in mice. Infect. Immun. 1990; 58: 2502-2509. 38. Cairo MS et al. Prophylactic or simultaneous administration of recombinant human granulocyte colony stimulating factor in the treatment of group B streptococcal sepsis in neonatal rats. Pediatr. Res. 1990; 27: 612-616. 39. Metcalf D et al. Role of granulocyte-macrophage colony-stimulating factor and granulocyte colony-stimulating factor in the development of an acute neutrophil inflammatory response in mice. Blood 1996; 88: 3755-3764. 40. Sherr CJ et al. Colony-stimulating factor-1 receptor. Blood 1990; 75: 1-12. 41. Fukunaga R et al. Purification and characterization of the receptor for murine granulocyte colony-stimulating factor. J. Biol. Chem. 1990; 265: 14008-14015. 42. Gearing DP et al. Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor. EMBO J. 1989; 8: 3667-3676. 43. Kitamura T et al. Expression of the human IL-3 receptor cDNA reveals a shared beta subunit for the human IL-3 and GM-CSF receptors. Cell 1991; 66: 1165-1174. 44. Tavernier J et al. A human high affinity interleukin-5 receptor (IL5R) is composed of an IL5-specific alpha chain and a beta chain shared with the receptor for GM-CSF. Cell 1991; 66: 1175-1184. 45. Fukunaga R et al. Growth and differentiation signals mediated by different regions in the cytoplasmic domain of granulocyte-stimulating factor receptor. Cell 1993; 74: 1079-1087. 46. Smith et al. Cytoplasmic domains of the common beta-chain of the GM-CSF/IL-3/IL-5 receptors that are required for inducing differentiation or clonal suppression in myeloid leukaemic cell lines. EMBO J. 1997; 16: 451-464. 47. McArthur GA et al. Induced expression of c-fms in normal hematopoietic cells shows evidence for both conservation and lineage restriction of signal transduction in response to macrophage colony-stimulating factor. Blood 1994; 83: 972-981. 48. Rohrschneider LR and Metcalf D. Induction of macrophage colony-stimulating factor-dependent growth and differentiation after introduction of the murine c-fms gene into FDC-P1 cells. Mol. Cell. Biol. 1989; 9: 5081-5092. 49. Evans CA et al. Activation of granulocyte-macrophage colony-stimulating factor and interleukin-3 receptor subunits in a multipotential hematopoietic progenitor cell line leads to differential effects on development. Blood 1999; 94: 1504-1514. 50. Fairburn LJ et al. Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors. Cell 1993; 74: 823-832. 51. Lieschke GJ et al. Mice lacking granulocyte colony-stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil mobilization. Blood 1994; 84: 1737-1746. 52. Yoshida H et al. The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene. Nature 1990; 345: 442-444. 53. Wiktor-Jedrzejczak W et al. CSF-1 deficiency in the op/op mouse has differential effects on macrophage populations and differentiation stages. Exp. Hematol. 1992; 20: 1004-1010. 54. Stanley E et al. Granulocyte/macrophage colony-stimulating factor-deficient mice show no major perturbation of hematopoiesis but develop a characteristic pulmonary pathology. Proc. Natl. Acad. Sci. USA 1994; 91: 5592-5596. 55. Dranoff G et al. Involvement of granulocyte-macrophage colony-stimulating factor in pulmonary homeostasis. Science 1994; 264: 713-716. 56. Seymour JF et al. Mice lacking both granulocyte colony-stimulating factor (CSF) and granulocyte-macrophage CSF have impaired reproductive capacity, perturbed neonatal granulopoiesis, lung disease, amyloidosis, and reduced long-term survival. Blood 1997; 15: 3037-3049. 57. Mach N et al. Involvement of interleukin-3 in delayed-type hypersensitivity. Blood 1998; 91: 778-783. 58. Ruscetti FW et al. Reduced blood and marrow neutrophils and granulocytic colony-forming cells in Sl/Sld mice. Proc. Soc. Exp. Biol. Med. 1976; 152: 398-402. 59. Lang RA et al. Transgenic mice expressing a hemopoietic growth factor gene (GM-CSF) develop accumulations of macrophages, blindness and a fatal syndrome of tissue damage. Cell 1987; 51: 675-686. 60. Metcalf D and Moore JG. Divergent disease patterns in GM-CSF transgenic mice associated with differing transgene insertion sites. Proc. Natl. Acad. Sci. USA 1988; 85: 7767-7771. 61. Chang JM et al. Non-neoplastic hematopoietic myeloproliferative syndrome induced by dysregulated Multi-CSF (IL-3) expression. Blood 1989; 73: 1487-1497. 62. Welte K et al. Filgrastim (r-metHuG-CSF): The first 10 years. Blood 1996; 88: 1907-1929. 63. Armitage JO. Emerging applications of recombinant human granulocyte-macrophage colony-stimulating factor. Blood 1998; 92: 4491-4508. 64. Dale DC et al. Randomized controlled Phase III trial of recombinant human granulocyte colony-stimulating factor (Filgrastim) for treatment of severe chronic neutropenia. Blood 1993; 81: 2496-2502. 65. Körbling M. Peripheral blood stem cells for allogeneic transplantation. In Hematopoietic Cell Transplantation. Thomas ED, Blume KG, Forman SJ eds. Blackwell Science Malden MA, 1994; 469-480. 66. Inaba K et al. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 1992; 176: 1693-1702. 67. Murray PJ et al. Manipulation and potentiation of antimycobacterial immunity using recombinant bacille Calmette-Guerin strains that secrete cytokines. Proc. Natl. Acad. Sci. USA 1996; 93: 934-939. 68. Caspar CB et al. Idiotype vaccines for non-Hodgkin’s lymphoma induce polyclonal immune responses that cover mutated tumor idiotypes: comparison of different vaccine formulations. Blood 1997; 90: 3699-3706.

 

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