Year XVI -Issue. 07 - 2000

 

 

 

 

 

Marco Margnelli

CURRICULUM

1/5

If we compare the brain to computer hardware, the states of consciousness represent its operating programs. These are no more than patterns for the processing of data, and can only work if they are compatible with a basic language which, in turn, is a code capable of organising the data supplied by the individual programs. Within the structure of consciousness, the basic language can be viewed as the ancestral memory, holding remembrances of the individual sensations or of the single basic operating schemes, based on which it has been possible to learn the language and build an "interior model of the physical world".

Although approximate, and therefore inaccurate, as are all the technological metaphors which attempt to describe biological structures, nevertheless this comparison is certainly useful to understand a subject, that is consciousness, which in the last fifty years has forcefully imposed itself on the attention of neurobiologists.

This interest can be said to have began in the forties, when Albert Hofmann, in the Roche laboratories, in Switzerland, discovered and synthesized the lysergic acid diethylamide, which subsequently became very well known by the acronym LSD. Till then, consciousness had only been a field of philosophical speculation and a subject of little interest for psychology.

LSD suddenly disclosed extraordinary connections between the neuronal hardware and the mental software, thus suggesting that consciousness is somehow a product of the activity of neurons and of chemical relations set up among them. The neuroscientific importance of consciousness, of its structure and of its modified states, had already been amply perceived during the last century by the Salpetrière clinicians, by the school of Jean Marie Charcot, by the founder of psychoanalysis, Sigmund Freud, by a number of experimental psychologists like William James and, above all, by Pierre Janet.

Somehow, with the success and the diffusion of the psychoanalytic theory, it appeared that the unconscious was more significant than consciousness, and the latter subject faded into the background. Undoubtedly, the initial interest arose because Charcot and all his followers (including Freud) used and practised hypnosis, a condition which today could be defined as the chief of many modified states of consciousness ("modified" sounds much better than "altered", as one often reads; and besides, the English word "altered" is the exact translation of the Italian word "modificati"); this is why they had been in some way forced to direct their attention to the structure of consciousness in order to understand the modifications experienced in a state of trance.

Anyhow Charcot was a clinician, essentially interested in the pathogenesis of diseases, and although he was able to reproduce the symptoms of a neurosis by putting his patients into a state of trance, he was never able to demonstrate the causal connections between the modifications of the state of consciousness and the pathogenesis of neuroses. However, the great interest for this aspect was shared by all those who attended his famous "Tuesday lectures" and, amongst all, the person who succeeded in constructing a satisfactory aetiological theory of neuroses was Freud, with his concept of "pathogenic unconscious" which, although weakened nowadays, has not yet been replaced by a more valid theory. Even though they spent the rest of their carriers working on the ideas of their master, the other followers of Charcot have either been forgotten or are now remembered for other merits.

Babinski, for instance, is known for his "sign" (extension of the hallux as a reaction to friction on the side of the foot) rather than for the fact that he (rightly) supported the idea that hysteric neurosis is a psychiatric disorder and not a neurological syndrome (as Charcot had claimed for years).

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Marco Margelli

 

Albert Hofmann

 

Jean Marie Charcot duranet una lezione

 

Sigmund Freud