Prof. Claudio Pignata, February 6, 1952, Naples, Italy
Education:
1971: graduated, High School “Umberto I”, Naples
1977: M.D. graduated, II Faculty of Medicine, University of Naples, Italy
Licensures and certifications:
1980: Postdoctoral School of Pediatrics, University of Naples (Residency in Pediatrics).
1983: Postdoctoral School of Child Health, University of Naples (Residency in Child Health).
1987: Ph.D. in Gastroenterology, Department of Pediatrics, Section “Immunology of the Gut”, University of Naples.
Academic appointments
1977-1978: Instructor (“Assistente volontario”), Departemnt of Pediatrics, University of Naples.
1978-1979: Research fellow, Department of Pediatrics-Section Clinical Immunology, University of Pavia.
1979-1983: Clinical and Research Fellow, Department of Pediatrics, University of Naples.
1983-1987: Ph.D. Fellowship, Department of Pediatrics, University of Naples.
1987-1990: Assistant Professor (Ricercatore Universitario), University of Reggio
Calabria.
1990: Research Fellow, Pediatric Immunology and Allergology, Children’s Hospital,
Harvard University, Boston, Massachussets.
1991-1993: Research Associate, Dana Farber Cancer Institute, Division of Tumor Immunology, Harvard University, Boston, Massachussets.
1993-2001: University Researcher, “Federico II” University, Naples
2001-2002: Associate Professor of Pediatrics, “Federico II” University, Naples
2003 present: Director of the “Pediatric Immunology” Department Area, “Federico
II” University, Naples.
Honours and Services
M.D. degree “magna cum laude”, University of Naples.
Residency in Pediatrics “magna cum laude”, University of Naples.
Residency in Child Health “magna cum laude”, University of Naples.
1987-1990: Integrative teaching activity, Institute of Pediatrics, University of Reggio Calabria.
1990: Consensus Conference on IgA deficiency in childhood, Capri.
Integrative teaching activity, Institute of Pediatrics, University of Naples.
2002-present: Associate Professor of Pediatrics, “Federico II”, University of Naples
Member of Societies
Italian Society of Pediatrics. - Italian Society of Immunology and Immunopathology.
- Italian Group of Pediatric Immunology and Allergology (Member of the Council). - European Society of Immunodeficiencies (ESID).
List of selected publications
1. Pignata C., Sanghera J.S., Soiffer R.J., Chartier S., Mathias Eder M., Steven L.
Pelech S.L., Ritz J. Defective activation of mitogen-activated protein kinase following allogeneic bone marrow transplantation. Blood 88: 2334-2341, 1996.
2. Pignata C., Fiore M., Scotese I., Cosentini E., M.P. Sperandeo, C. Turco, A. Petrella, Notarangelo L., Venuta S. Combined immunodeficiency phenotype associated with inappropriate spontaneous and activation-induced apoptosis. Clin. Exp. Immunol. 108:484-489, 1997.
3. Pignata C., Fiore M., de Filippo S., Cavalcanti M., Gaetaniello L., Scotese I. Apoptosis as a mechanism of peripheral blood mononuclear cell death following measles and varicella-zoster virus infections in children. Ped. Res. 43: 77-83, 1998
4. Frank J., Pignata C., Panteleyev A.A., Prowse D.M., Baden H., Weiner L., Gaetaniello L., Ahmad W., Pozzi N., Cserhalmi-Friedman P.B., Gordon D., Ott J., Brissette J.L., Christiano A.M. Exposing the human nude-fenotype. Nature 398: 473-474, 1999.
5. Pignata C., Gaetaniello L., Masci A.M., Frank J., Christiano A., Matrecano E., Racioppi L. Human equivalent of the mouse nude/SCID phenotype: Long-term evaluation of immunological reconstitution after bone marrow transplantation. Blood 97: 880-5, 2001.
6. DeFranco S., Bonissoni S., Cerutti F., Bona G., Bottarel F., Cadario F., Brusco A., Loffredo G., Rabbone I., Corrias A., Pignata C., Ramenghi U., Dianzani U. Defective function of Fas in patients with type 1 diabetes associated with other autoimmune diseases. Diabetes 50: 483-8, 2001
7. Lopez Granados E., Porpiglia A.S., Hogan M.B., Matamoros N., Krasovec S., Pignata C., Smith C.I., Hammarstrom L., Bjorkander J., Belohradsky B.H., Casariego G.F. Garcia Rodriguez M.C. Conley M.E. Clinical and molecular analysis of patient with defects in micro heavy chain gene. J. Clin. Invest. 110: 1029-1035, 2002.